カワサキ ヒロアキ    KAWASAKI Hiroaki
   川崎 広明
   所属
生活科学部 管理栄養学科
   職種
専任講師
言語種別 英語
発行・発表の年月 2014/08
形態種別 学術雑誌
査読 査読あり
標題 Importance of tryptophan nitration of carbonic anhydrase III for the morbidity of atopic dermatitis.
執筆形態 共著
掲載誌名 Free Radic. Biol. Med.
掲載区分国外
巻・号・頁 73,pp.75-83
著者・共著者 Kawasaki H,Tominaga M, Shigenaga A, Kamo A, Kamata Y, Iizumi K, Kimura U, Ogawa H, Takamori K, Yamakura F.
概要 In this study, we revealed that carbonic anhydrase III (CAIII) was nitrated in the skin region of atopic dermatitis (AD) model mice and AD patient. In addition to that, the enzyme activity of CAIII was suppressed by the nitration. So we considered that the nitration of CAIII might be critical factor to induce AD conditions such as alkalization of skin surface.