ムラヤマ ノリオ    Murayama Norio
   村山 憲男
   所属
人間社会学部 心理学科
 
生活機構研究科 心理学専攻
 
生活心理研究所 所属教員
 
生活機構研究科 生活機構学専攻
   職種
准教授
言語種別 英語
発行・発表の年月 2013/02
形態種別 学術雑誌
査読 査読あり
標題 Neuropsychological detection of the early stage of amnestic mild cognitive impairment without objective memory impairment
執筆形態 共著
掲載誌名 Dementia and Geriatric Cognitive Disorders
掲載区分国外
巻・号・頁 35,pp.98-105
著者・共著者 ◎Norio MURAYAMA, Eizo ISEKI, Hirokuni TAGAYA, Kazumi OTA, Koji KASANUKI, Hiroshige FUJISHIRO, Heii ARAI, Kiyoshi SATO
概要 Aim: We investigate the assessment method to detect the early stage of amnestic mild cognitive impairment (aMCI) using Wechsler Memory Scale - Revised (WMS-R) and Wechsler Adult Intelligence Scale - Third Edition (WAIS-III).
Methods: Three groups (normal group, aMCI group, and early aMCI group), controlled for age and years of education, underwent brain (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET), WAIS-III, WMS-R, and other tests. The early aMCI group does not fulfill the clinical diagnostic criteria of aMCI because patients do not have objective memory impairment, but their clinical symptoms and results of (18)F-FDG PET indicate that they should be included in the category of aMCI.
Results: The discrepancy of scores between Verbal IQ and General Memory had the highest accuracy in discriminating between normal and early aMCI groups.
Conclusion: The cutoff point determined in this study is useful to detect an early stage of aMCI, which may be distinguished from aMCI using the current criteria.