イケダ タカコ
IKEDA Takako
池田 尚子 所属
食健康科学部 健康デザイン学科
女性健康科学研究所 所属教員
職種
准教授
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言語種別 | 英語 |
発行・発表の年月 | 2000/09 |
形態種別 | 学術雑誌 |
査読 | 査読あり |
標題 | Lack of Modifying effects of environmental estrogenic compounds on the development of thyroid proliferative lesions in male rats |
執筆形態 | 共著 |
掲載誌名 | Jpn.J.Cancer Res.91 |
掲載区分 | 国内 |
巻・号・頁 | pp.899-905 |
著者・共著者 | ◎Son.H.Y.,A.Nishikawa,T.Ikeda,H.Nakamura,M.Miyauchi,T.Imazawa,F.Furukawa,M.Hirose |
概要 | The modifying effects of various environmental estrogenic compounds on thyroid carcinogenesis were investigated in a rodent two-stage carcinogenesis model. The compounds examined were a soy isoflavone mixture (SI) and genistein (GEN) as phytoestrogens, nonylphenol (NP) as a xenoestrogen, 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) as a thyroid carcinogen and sulfadimethoxine (SDM) as a known thyroid tumor promoter. Our results thus indicate that the weakly estrogenic compounds GEN, SI and NP and the environmental rat thyroid carcinogen MX do not exert any modifying effects on thyroid carcinogenesis in rats under the present experimental conditions. |