イケダ タカコ
IKEDA Takako
池田 尚子 所属
食健康科学部 健康デザイン学科
女性健康科学研究所 所属教員
職種
准教授
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言語種別 | 英語 |
発行・発表の年月 | 2001/03 |
形態種別 | 学術雑誌 |
査読 | 査読あり |
標題 | Induction of pancreatic islet cell tumors in rats by repeated intravenous administration of 4-hydroxyaminoquinoline 1-oxide |
執筆形態 | 共著 |
掲載誌名 | Toxicol pathol. 29 (3) |
掲載区分 | 国外 |
巻・号・頁 | pp.320-327 |
著者・共著者 | ◎T.Imazawa,A.Nishikawa,M.shibutani,H.Ogasawara,F.Furukawa,T.Ikeda,K.Suda,M.Hirose |
概要 | The inducibility of pancreatic islet cell tumors by administration of 4-hydroxyaminoquinoline 1-oxide (4HAQO) was investigated in male 6-week-old Sprague-Dawley rats. Rats were given 4HAQO intravenously at a weekly dose of 5 mg/kg 4 times (group 1) or a single dose of 10 mg/kg (group 2). Thus our results indicate that repeated intravenous administration of 4HAQO to rats is useful for the induction of islet cell tumors at high incidence. |