イケダ タカコ    IKEDA Takako
   池田 尚子
   所属
食健康科学部 健康デザイン学科
 
女性健康科学研究所 所属教員
   職種
准教授
言語種別 英語
発行・発表の年月 2001/03
形態種別 学術雑誌
査読 査読あり
標題 Induction of pancreatic islet cell tumors in rats by repeated intravenous administration of 4-hydroxyaminoquinoline 1-oxide
執筆形態 共著
掲載誌名 Toxicol pathol. 29 (3)
掲載区分国外
巻・号・頁 pp.320-327
著者・共著者 ◎T.Imazawa,A.Nishikawa,M.shibutani,H.Ogasawara,F.Furukawa,T.Ikeda,K.Suda,M.Hirose
概要 The inducibility of pancreatic islet cell tumors by administration of 4-hydroxyaminoquinoline 1-oxide (4HAQO) was investigated in male 6-week-old Sprague-Dawley rats. Rats were given 4HAQO intravenously at a weekly dose of 5 mg/kg 4 times (group 1) or a single dose of 10 mg/kg (group 2). Thus our results indicate that repeated intravenous administration of 4HAQO to rats is useful for the induction of islet cell tumors at high incidence.