コニシ カナエ KONISHI Kanae
|標題||Prenatal exposure to perfluorinated chemicals and relationship with allergies and infectious diseases in infants.|
|著者・共著者||Emiko Okada, Seiko Sasaki, Yasuaki Saijo, Noriaki Washino, Chihiro Miyashita, Sumitaka Kobayashi, Kanae Konishi, Yoichi M.Ito, Rie Ito, Ayako Nakata, Yusuke Iwasaki, Koichi Saito, Hiroyuki Nakazawa, Reiko Kishi|
|概要||To investigate the relationship between maternal PFOS and PFOA levels and infant allergies and infectious diseases during the first 18 months of life. Cord blood immunoglobulin (Ig) E levels were also evaluated.
Methods: We conducted a prospective cohort study of pregnant women from 2002 to 2005 in Sapporo, Japan. Maternal PFOS and PFOA levels were measured in relation to cord blood IgE concentrations (n=231) and infant allergies and infectious diseases (n=343).
Results: Cord blood IgE levels decreased significantly with high maternal PFOA concentration among female infants. However, there were no significant associations among maternal PFOS and PFOA levels and food allergy, eczema, wheezing, or otitis media in the 18 month-old infants.