ウメガキ ケイゾウ    UMEGAKI Keizo
   梅垣 敬三
   所属
生活科学部 食安全マネジメント学科
 
生活機構研究科 生活科学研究専攻
   職種
教授
言語種別 英語
発行・発表の年月 1992
形態種別 学術雑誌
査読 査読あり
標題 Phospholipid metabolism in platelets from stroke-prone spontaneously hypertensive rats and Wistar Kyoto rats.
執筆形態 共著
掲載誌名 J Pharmacobiodyn
掲載区分国外
巻・号・頁 15(2),pp.49-57
著者・共著者 Ikeda, M., T. Onda, T. Mitsubori, Umegaki K, I. Tomita, and T. Tomita
概要 Platelets from stroke-prone spontaneously hypertensive rats (SHRSP) show severe hypofunctions accompanied by defective protein (P47) phosphorylation. The results suggest that reduced formation of diacylglycerol, an activator of protein kinase C (PKC), does not cause defective phosphorylation of P47, a substrate of PKC, in SHRSP. However it remains unclear how the lower PI content and the altered distribution of AA in PC and PE is related to SHRSP platelet hypofunctions.