ウメガキ ケイゾウ    UMEGAKI Keizo
   梅垣 敬三
   所属
生活科学部 食安全マネジメント学科
 
生活機構研究科 生活科学研究専攻
   職種
教授
言語種別 英語
発行・発表の年月 1989
形態種別 学術雑誌
査読 査読あり
標題 Changes in platelet function due to hypertension: comparison of experimental hypertension with spontaneous hypertension in rats.
執筆形態 共著
掲載誌名 J Hypertens
掲載区分国外
巻・号・頁 7(1),pp.13-19
著者・共著者 ◎Umegaki, K., K. Nakamura, M. Ikeda, Y. Inoue, and T. Tomita
概要 In washed platelets both from DOCA-salt and renal hypertensive rats, there was a marked decrease in thrombin-induced aggregation and secretion responses compared with those of respective controls.The results suggest that the mechanisms of platelet hypofunction differ between experimental hypertension and spontaneous hypertension in their early stages. The hypo-aggregability observed in experimental hypertension appears to be secondary to the hypertension, whereas that seen in spontaneous hypertension seems to be a primary defect and not secondary to hypertension at early stages of hypertension.