ウメガキ ケイゾウ    UMEGAKI Keizo
   梅垣 敬三
   所属
生活科学部 食安全マネジメント学科
 
生活機構研究科 生活科学研究専攻
   職種
教授
言語種別 英語
発行・発表の年月 1982
形態種別 学術雑誌
査読 査読あり
標題 Sex differences in aortic cholesterol esterase activity in rats, and changes of the activity following castration and gonadal hormone treatment.
執筆形態 共著
掲載誌名 Atherosclerosis
掲載区分国外
巻・号・頁 43,pp.405-415
著者・共著者 Tomita, T., I. Yonekura, Umegaki K, T. Okada, and E. Hayashi
概要 Sex differences in aortic cholesterol esterase activity and changes in the activity following castration and gonadal hormone treatment were investigated in rats. The results suggest (1) that there are clear sex differences in aortic cholesterol esterase activity, (2) that prepubertal exposure to androgens plays a critical role in the sexual differentiation in aortic and hepatic cholesterol ester metabolism, and (3) that the administration of testosterone can temporarily masculinize the type of metabolism. These results partly explain the sexual differences in susceptibility to atherosclerosis.