ウメガキ ケイゾウ    UMEGAKI Keizo
   梅垣 敬三
   所属
生活科学部 食安全マネジメント学科
 
生活機構研究科 生活科学研究専攻
   職種
教授
言語種別 英語
発行・発表の年月 2013
形態種別 学術雑誌
査読 査読あり
標題 Influence of dietary macronutrients on induction of hepatic drug metabolizing enzymes by Coleus forskohlii extract in mice.
執筆形態 共著
掲載誌名 J Nutr Sci Vitaminol
掲載区分国外
巻・号・頁 59(1),pp.37-44
著者・共著者 Yokotani, K., Chiba, T., Sato, Y., Nakanishi, T., Murata, M., Umegaki K
概要 This study was designed to examine how the induction of drug metabolizing enzymes by CFE was influenced by different levels of macronutrients in the diet. The effect of CFE on the ratio of liver weight to body weight was higher with a semi-purified diet than with a non-purified diet, and was similar between dietary administration and intragastric gavage when the CFE dose and the diet were the same. There was a positive correlation between CFE-induced CYP induction and the content of starch in the diets, suggesting that dietary starch potentiates CFE-induced CYP induction in mice.