ムラマツ シュキ    MURAMATSU Shuki
   村松 朱喜
   所属
食健康科学部 健康デザイン学科
 
女性健康科学研究所 所属教員
   職種
専任講師
発表年月日 2012/07
発表テーマ Epigenetic regulation involved in ethanol stress response in Saccharomyces cerevisiae.
発表学会名 Yeast Genetics & Molecular Biology Meeting
学会区分 国際学会
発表形式 ポスター
単独共同区分 共同
開催地名 Princeton, US
発表者・共同発表者 Fujimura S., Matsuda T., Suda H. and Nakagawa J.
概要 Eukaryotic cells encounter various environmental stresses that can cause growth inhibition or cell death. During fermentation process, yeast cells are exposed to various stresses such as oxidative, high sugar content, starvation and ethanol. Ethanol stress is one of the most common stresses and the cells should be equipped with appropriate mechanisms to avoid resulting damages. It has been shown that the expression of some genes is modified in response to ethanol. Among candidate genes involved in the ethanol stress response, we focused on the epigenetic regulation that is known as the gene regulatory mechanism through chromatin remodeling. ...In summary, it was demonstrated that HDACs and epigenetic factors are involved in the stress response against ethanol and other stresses. It would be worthwhile to further investigate the relationship between histone acetylation and expression pattern of the genes that alter in accordance with ethanol stress condition.