イイノ ヒサカズ    IINO Hisakazu
   飯野 久和
   所属
食健康科学部 管理栄養学科
 
生活機構研究科 生活科学研究専攻
 
生活機構研究科 生活機構学専攻
   職種
教授
発表年月日 2016/11/28
発表テーマ Gut microbiota associated with blood parameters and affected by probiotics during the Japanese cedar pollen season
発表学会名 5th Asian Federation of societies for Lactic Acid Bacteria International Symposium
主催者 Asian Federation of societies for Lactic Acid Bacteria
学会区分 国際学会
発表形式 ポスター
単独共同区分 共同
開催地名 Taipei, TAIWAN
発表者・共同発表者 Gaku Harata, Himanshu Kumar, Fang He, Kenji Miyazawa, Kazutoyo Yoda, Masaru Hiramatsu, Samuli Rautava, Seppo Salminen
概要 This study is the first observation of the correlation between the gut microbiota and blood lipid and immunological parameter in JCP. Faecal samples from JCP subjects were collected before and after treatment with (n = 14) and without (n = 11) LGG–TMC0356-fermented milk for 10 weeks. Gut microbiota composition was characterised from fecal DNA using sequencing of 16S rRNA genes. 16S rRNA-based operational taxonomic unit clustering of the microbiota revealed that LGG–TMC0356-fermented milk significantly altered gut microbiota after 10 weeks of milk consumption, and eight dominant genera of microbes were detected. Interestingly, after consumption fermented milk at genus Bacteroides, the abundance were positively correlated with fecal IgA and anti-Japanese cedar pollen IgE. During the JCP season, the Bacteroidetes/Firmicutes ratio, when compared to baseline, was significantly decreased in subjects at end of the study.